The research group of prof. Steve Stegen is part of the Clinical and Experimental Endocrinology Lab, at the Department of Chronic Diseases and Metabolism. Our research focus is to understand how the specific metabolic profile of skeletal cells regulates their function and how deregulated metabolic pathways cause bone pathologies, in order to provide new therapeutic opportunities.
Project
You will work on an exciting new project, which aims to investigate how metabolic reprogramming causes skeletal cell dysfunction during osteoporosis. To tackle our specific research questions, you will use preclinical mouse models of metabolically induced bone loss, combined with state-of-the-art technologies including single-cell RNA sequencing, metabolomics, multi-color flow cytometry, imaging and genetic engineering to gain deep mechanistic insights. You will take part in internal seminars and meetings to disseminate your findings, and attend relevant workshops and training courses.
Profile
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- You hold a Master’s degree in Biomedical Sciences, Bioengineering or a related discipline
- Hands-on experience with laboratory animals, cell culture and biochemical assays such as Western blot and qRT-PCR analysis is certainly desired, but not all is required. Some experience with bioinformatics would be a plus
- You are a proactive, dynamic person and show spirit for initiative and problem-solving
- You take great care and precision in your work, and are able to work independently but also as part of a team
- You possess excellent oral and written communication skills in English
Offer
- We offer a PhD position in a young and dynamic team within an excellent working environment
- You will have the opportunity to work on high impact projects in a multidisciplinary environment with access to state-of-the-art technologies and infrastructure
- We support PhD students with excellent (daily) guidance and training, and provide the opportunity to participate in (inter)national collaborations and conferences
- We aspire to create a lab culture where all talents can flourish and feel welcome, regardless of age, race, gender, cultural background or disability
Interested?
Please send your application to prof. Steve Stegen at steve.stegen@kuleuven.be. The application should include: 1) a CV including previous research experience, 2) a short cover letter describing your motivation, research interests and career objectives.
You can apply for this job no later than August 31, 2023 via the online application tool
KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.
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